Phospholipid actions on PGHS-1 and -2 cyclooxygenase kinetics
نویسندگان
چکیده
منابع مشابه
Prostaglandin (PG) endoperoxide synthase (PGHS)-1 and PGHS-2 catalyze the formation of PGH2 from arachi-
Journal of Lipid Research Volume 57, 2016 1043 Copyright © 2016 by the American Society for Biochemistry and Molecular Biology, Inc. (1–4). PGHS-1 and PGHS-2 are considered to be the constitutive and inducible PGHS isoforms, respectively. PGHSs are often called cyclooxygenases (COXs). Both enzymes exhibit a bis-oxygenase or COX activity involved in the formation of the PG endoperoxide G2 and a ...
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Aspirin eugenol ester (AEE) is a promising drug candidate, which is used for the treatment of inflammation, pain and fever and the prevention of cardiovascular diseases. This study focuses on the effect of AEE on five proteins which are related to inflammation and thrombosis, including cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2), C-reactive protein (CRP), prothrombin (FII) and arachidona...
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ژورنال
عنوان ژورنال: Prostaglandins & Other Lipid Mediators
سال: 2008
ISSN: 1098-8823
DOI: 10.1016/j.prostaglandins.2007.12.001